Center for Pediatric Oncology and Hematology

Center for Pediatric Oncology and Hematology

Clinical and Translational Research

200+ clinical trials, 1,000+ annual patients, 1 amazing team

As the largest cancer and blood disease program in North Texas, and one of the largest in the U.S., UT Southwestern physicians provide world-class care to more than 350 children with newly-diagnosed cancer and more than 600 children with newly-diagnosed blood disease each year at Children’s Health℠.

The Pauline Allen Gill Center for Cancer and Blood Disorders is a pediatric cancer program for the UT Southwestern Harold C. Simmons Comprehensive Cancer Center, the only National Cancer Institute-designated comprehensive cancer center in North Texas. As such we offer patients the ability to participate in the broadest possible range of clinical trials, giving them access to novel therapies not available at other facilities as we continue to advance the discovery of new treatments.

The Pauline Allen Gill Center for Cancer and Blood Disorders is the pediatric hematology center housing where UT Southwestern physicians have developed innovative clinical care and research programs such as the Young Women’s Blood Disorder program and the North Texas Sickle Cell Disease Clinical Trial Unit.

Further information on available novel therapies is readily available during clinic visits and through virtual tools such as the Simmons Cancer Center email, and Children’s Health clinical research trials list.

Our Clinical Trials Groups

  • Childrens Oncology Group (COG)
  • Pediatric Early Phase Clinical Trials Network (PEP-CTN), non-core members
  • The Neurofibromatosis (NF) Clinical Trials Consortium
  • Therapeutic Advances in Childhood Leukemia & Lymphoma Consortium (TACL)
  • Sunshine Consortium
  • ACCESS/REDIAL, Case Ascertainment for Epidemiologic Studies of Childhood Cancers and Hematological Conditions Used by Adolescent and Childhood Cancer Epidemiology and Susceptibility Service (ACCESS) for Texas and Reducing Ethnic Disparities in Acute Leukemias (REDIAL) Consortium
  • Gain (Genomic Assessment Informs Novel Therapy) Consortium


Heart doctors at Children's Health analyze a patient's imaging results

Clinical Trial Highlights

FUVID study – A multi-center prospective cohort study of patients with first-episode, deep-venous thrombosis and pulmonary embolism

  • Discover why physical complications happen after blood clots
  • Research and develop treatments for these problems

Learn more about this study 

VITAS trial – A study evaluating the feasibility and efficacy of vincristine, irinotecan, temozolomide and atezolizumab in children with relapsed/refractory solid tumors

  • Determine the objective response rate, duration of response and progression-free survival for all children

Learn more about this study


Latest News

Patrick Leavey, M.D., became Associate Director of Clinical Research at UT Southwestern Harold C. Simmons Comprehensive Cancer Center.

Ayesha Zia, M.D., Pediatric Hematologist/Oncologist at Children’s Health and Associate Professor at UT Southwestern, has been appointed as the Associate Vice Chair of Clinical Research for the Department of Pediatrics at UT Southwestern.

Laura Klesse, M.D., Pediatric Hematologist/Oncologist at Children's Health and Associate Professor at UT Southwestern, was named a Principal Investigator for the Pediatric Early Phase Clinical Trials Network.

Conferences and Events

Many of our conferences and events offer continuing education credits.

Save the date for the 2024 ASPHO Conference April 3-6, 2024 in Seattle, WA.

Meet the Care Team