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Avanthi Tayi Shah, MD $$

Pediatric Hematologist/Oncologist

Assistant Professor at UT Southwestern Medical Center

Languages Spoken:
English,

Locations

Virtual Visit Available

UT Southwestern Pediatric Group

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Education and Training

Medical School
University of Texas Southwestern Medical Center (2009)
Residency
UT Southwestern - Children's Medical Center (2012), Pediatrics
Fellowship
Standford University School of Medicine (2016), Pediatric Hematology/Oncology
Board Certification
American Board of Pediatrics/Hematology-Oncology

Conditions

  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Germ cell tumors
  • Glioma
  • Hodgkin Lymphoma
  • Iron Deficiency Anemia
  • Kidney cancer
  • Pineoblastoma
  • Primitive Neuroectodermal Tumor (PNET)

  • Research Interests

    • Precision Medicine Cancer Genetics Sarcoma

  • Publications

    • Genome-Informed Targeted Therapy for Osteosarcoma. Sayles LC, Breese MR, Koehne AL, Leung SG, Lee AG, Liu HY, Spillinger A, Shah AT, Tanasa B, Straessler K, Hazard FK, Spunt SL, Marina N, Kim GE, Cho SJ, Avedian RS, Mohler DG, Kim MO, DuBois SG, Hawkins DS, Sweet-Cordero EA. Cancer Discov. 2019 Jan;9(1):46-63. doi: 10.1158/2159-8290.CD-17-1152. Epub 2018 Sep 28.
    • Hydra: A mixture modeling framework for subtyping pediatric cancer cohorts using multimodal gene expression signatures. Pfeil J, Sanders LM, Anastopoulos I, Lyle AG, Weinstein AS, Xue Y, Blair A, Beale HC, Lee A, Leung SG, Dinh PT, Shah AT, Breese MR, Devine WP, Bjork I, Salama SR, Sweet-Cordero EA, Haussler D, Vaske OM. PLoS Comput Biol. 2020 Apr 10;16(4):e1007753. doi: 10.1371/journal.pcbi.1007753. eCollection 2020 Apr.
    • An Unusual Parotid Mass in a 14-Year-Old Female. Leavitt T, Shah AT, Singh V, Mitchell RB, Liu CC.  Ear Nose Throat J. 2021. Shah AT, Azad TD, Breese MR, Chabon JJ, Hamilton EG, Straessler K, Kurtz DM, Leung SG, Spillinger A, Liu HY, Behroozfard IH, Wittber FM, Hazard FK, Cho SJ, Daldrup-Link HE, Vo KT, Rangaswami A, Pribnow A, Spunt SL, Lacayo NJ, Diehn M, Alizadeh AA, Sweet-Cordero EA. A Comprehensive Circulating Tumor DNA Assay for Detection of Translocation and Copy-Number Changes in Pediatric Sarcomas. Mol Cancer Ther. 2021.
    • Shah AT, Azad TD, Breese MR, Chabon JJ, Hamilton EG, Straessler K, Kurtz DM, Leung SG, Spillinger A, Liu HY, Behroozfard IH, Wittber FM, Hazard FK, Cho SJ, Daldrup-Link HE, Vo KT, Rangaswami A, Pribnow A, Spunt SL, Lacayo NJ, Diehn M, Alizadeh AA, Sweet-Cordero EA. A Comprehensive Circulating Tumor DNA Assay for Detection of Translocation and Copy-Number Changes in Pediatric Sarcomas. Mol Cancer Ther. 2021 Oct;20(10):2016-2025. doi: 10.1158/1535-7163.MCT-20-0987. Epub 2021 Aug 5. PMID: 34353895; PMCID: PMC9307079.
    • Levinson A, Lee AG, Martell HJ, Breese MR, Zaloudek C, Van Ziffle J, Laguna B, Leung SG, Chen MD, Chen LM, Pfeil J, Ladwig NR, Shah AT, Behroozfard I, Rao AA, Salama SR, Sweet-Cordero EA, Stieglitz E. Complete Response to PD-1 Inhibition in an Adolescent With Relapsed Clear Cell Adenocarcinoma of the Cervix Predicted by Neoepitope Burden and APOBEC Signature. JCO Precis Oncol. 2020 Nov 2;4:PO.20.00132. doi: 10.1200/PO.20.00132. PMID: 33283136; PMCID: PMC7713560.
    • Vaske OM, Bjork I, Salama SR, Beale H, Tayi Shah A, Sanders L, Pfeil J, Lam DL, Learned K, Durbin A, Kephart ET, Currie R, Newton Y, Swatloski T, McColl D, Vivian J, Zhu J, Lee AG, Leung SG, Spillinger A, Liu HY, Liang WS, Byron SA, Berens ME, Resnick AC, Lacayo N, Spunt SL, Rangaswami A, Huynh V, Torno L, Plant A, Kirov I, Zabokrtsky KB, Rassekh SR, Deyell RJ, Laskin J, Marra MA, Sender LS, Mueller S, Sweet-Cordero EA, Goldstein TC, Haussler D. Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer. JAMA Netw Open. 2019 Oct 2;2(10):e1913968. doi: 10.1001/jamanetworkopen.2019.13968. PMID: 31651965; PMCID: PMC6822083.
    • Fernandez KS, Turski ML, Shah AT, Bastian BC, Horvai A, Hardee S, Sweet-Cordero EA. Ewing sarcoma in a child with neurofibromatosis type 1. Cold Spring Harb Mol Case Stud. 2019 Oct 23;5(5):a004580. doi: 10.1101/mcs.a004580. PMID: 31645347; PMCID: PMC6824249.
    • Sanders LM, Rangaswami A, Bjork I, Lam DL, Beale HC, Kephart ET, Durbin A, Learned K, Currie R, Lyle AG, Pfeil J, Shah AT, Lee AG, Leung SG, Behroozfard IH, Breese MR, Peralez J, Hazard FK, Lacayo N, Spunt SL, Haussler D, Salama SR, Sweet-Cordero EA, Vaske OM. Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor. Cold Spring Harb Mol Case Stud. 2019 Oct 23;5(5):a004317. doi: 10.1101/mcs.a004317. PMID: 31645344; PMCID: PMC6824255.
    • Tran TH, Shah AT, Loh ML. Precision Medicine in Pediatric Oncology: Translating Genomic Discoveries into Optimized Therapies. Clin Cancer Res. 2017 Sep 15;23(18):5329-5338. doi: 10.1158/1078-0432.CCR-16-0115. Epub 2017 Jun 9. PMID: 28600472.

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