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What is Osteosarcoma?

Osteosarcoma is a tumor that forms in osteoblasts, or cells that become new bone tissue. It is the most common bone cancer in children and teenagers.

What are the signs and symptoms of Osteosarcoma?

Early signs of osteosarcoma are pain and swelling in the affected area, which is most commonly the bones around the knee and shoulder. This cancer can spread, or metastasize, to other areas of the body, most often the lungs, if cancer cells enter the bloodstream. Osteosarcoma is curable in most children and adolescents. Patient specific prognosis depends on the tumor’s origin, size, stage and early response to treatment.

How is Osteosarcoma treated?

After being diagnosed with osteosarcoma, treatment options include chemotherapy to systemically destroy cancerous cells and surgery to remove the tumor mass. Your child’s physician will consider the size and location of the cancer, your child’s age and overall health, and whether the cancer has spread in order to develop the best treatment for your child.

We are leading a multi-institutional study to use advanced computer science to develop a novel biomarker in osteosarcoma and pattern detection to identify characteristics of cancerous bone tumors that predict therapy response. The goal is to gather information for early and better decision-making on treatment options. A number of families travel to our facility for treatment because of our leading therapies backed by the latest research.

Many children with osteosarcoma are treated with therapy as part of ongoing clinical trials. Physicians at Children’s Health lead the development of such advanced therapy through trials initiated at UT Southwestern and Children’s Health, those of the Children’s Oncology Group and other groups. This allows patients to receive cutting-edge therapies available at few hospitals in the U.S.

Children’s Health is staffed by expert and experienced pediatric oncologists, surgeons and subspecialists. The Pauline Allen Gill Center for Cancer and Blood Disorders is a world-class and nationally recognized leader in pediatric cancer. If your child has been diagnosed with osteosarcoma or you want an expert second opinion, turn to pediatric tumor specialists who can manage the complex bone cancer.

Osteosarcoma Doctors and Providers