What are Pediatric Neuromuscular Disorders?
Children with neuromuscular diseases have problems with the nerves and muscles that affect how their muscles work. They may affect the nerves that control different kinds of muscles, the muscles themselves or the way that the nerves and muscles communicate with each other. Some of these conditions are inherited (passed from parent to child), but others have other causes. These disorders typically cause muscle weakness. Usually, the symptoms slowly get worse over time.
What are the different types of Pediatric Neuromuscular Disorders?
There are many different types of neuromuscular disorders including:
Congenital muscular dystrophy
Congenital muscular dystrophy is a group genetic disorder that causes muscles to get weaker and weaker over time.
Congenital myopathies are genetic diseases that cause muscle weakness that can be mild to severe.
This condition causes problems with the nervous system and movement.
Limb-girdle muscular dystrophies
Limb-girdle muscular dystrophies are rare disorders with muscle-wasting (weakening, shirking and loss of muscles) in the hips and shoulders.
This type of muscular dystrophy begins in adulthood and can be seen as a congenital, childhood or adult form.
Neuromuscular junction disorders
Neuromuscular junction disorders affect the area where nerves connect to muscles. Myasthenia gravis, botulism and congenital myasthenic syndrome are neuromuscular junction disorders.
Neuropathies are problems with the nerves that can cause numbness, tingling, pain and other symptoms. Acquired neuropathies include Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, diabetic neuropathy and toxic neuropathies. Hereditary neuropathies include Charcot-Marie-Tooth disease (CMT).
Spinal muscular atrophy
This condition makes it hard for a child to control their muscle movement. The main problem is in the motor nerve cells located in the spine.
What causes Pediatric Neuromuscular Disorders?
These conditions have a range of causes. Some are inherited, while others are not. Some may be caused by other diseases, or they may be due to an autoimmune reaction where the body’s immune system attacks itself. Some are caused by injuries, including injuries at birth.