Our commitment to keeping you safe

We have never taken for granted the sacred trust you place in us to care for your child, and today we are more grateful than ever for that privilege. To learn about all the ways we are working to keep you, your family and our team members safe, visit our COVID-19 updates page.

Thymectomy for Pediatric Myasthenia Gravis

Thymectomy for Pediatric Myasthenia Gravis causes weakness and rapid fatigue of the muscles over which a child normally has control.

What is Thymectomy for Pediatric Myasthenia Gravis?

Myasthenia gravis is an autoimmune disease that affects some nerve signals to the muscles, making them weaker. Although it can happen at any age, myasthenia gravis is extremely rare in children. Symptoms are the same in children and adults. In most cases, the neonatal form of the condition is due to an affected mother's abnormal antibodies interfering with her unborn baby's nerve impulses. Symptoms of myasthenia gravis in infants usually disappear within two to three months after birth.

What are the signs and symptoms of Thymectomy for Pediatric Myasthenia Gravis?

In addition to muscle weakness, children with myasthenia gravis can experience:

  • Change in their speaking voice
  • Difficulty chewing, swallowing or frequent choking while eating or drinking
  • Double vision (diplopia)
  • Drooping of one or both eyelids (ptosis)
  • Reduced facial expressions

Symptoms vary depending on the severity of the condition and tend to improve with rest and worsen with activity. 

How is Thymectomy for Pediatric Myasthenia Gravis diagnosed?

The thymus gland plays a significant role in the development of a child's immune system. Although researchers don't fully understand the connection, it's generally believed that myasthenia gravis is the result of the thymus gland providing incorrect instructions to developing immune cells.

Because muscle weakness is a symptom of several conditions, myasthenia gravis can be hard to diagnose. If a doctor suspects the condition, there are several tests available to confirm a diagnosis. They include:

  • Blood tests (to detect immune molecules or acetylcholine receptor antibodies)
  • Diagnostic imaging (a CT Scan or an MRI can identify problems with the thymus)
  • Edrophonium test (uses edrophonium chloride to briefly relieve muscle weakness in a patient)
  • Nerve conduction (repetitive nerve stimulation tests for "fatigue" in specific muscles)
  • Pulmonary function testing (measures breathing strength)
  • Single fiber electromyography (detects impaired nerve-to-muscle transmission)

How is Thymectomy for Pediatric Myasthenia Gravis treated?

Treatments for myasthenia gravis include medications that prevent the body from making too many abnormal antibodies or improve connections between the nerves and muscles.

Other treatments may filter out abnormal antibodies or rely on donated blood to introduce healthy ones. With the right treatment, symptoms usually improve significantly or disappear completely. Myasthenia gravis may also go into remission for some children.

Thymectomy for Pediatric Myasthenia Gravis Doctors and Providers