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Lennox-Gastaut Syndrome

Lennox-Gastaut syndrome is a rare, debilitating form of epilepsy that causes seizures, cognitive impairment and abnormal brain activity.

What is Lennox-Gastaut Syndrome?

Lennox-Gastaut syndrome is a rare and often debilitating type of epilepsy that usually first appears between the ages of 2 and 6. Due to its unique combination of symptoms, this condition is one of the most challenging forms of epilepsy to treat. What’s more, Lennox-Gastaut syndrome is a dangerous condition due to the frequent falls, injuries and cognitive (thinking) impairment that can impact the child’s quality of life.

What are the signs and symptoms of Lennox-Gastaut Syndrome?

  • Mood instability
  • Personality disturbances
  • Poor social skills and attention seeking behavior
  • Seizures

What are the causes of Lennox-Gastaut Syndrome?

In 20 to 30 percent of cases, there is no known cause of this condition. Some of the known causes of Lennox-Gastaut syndrome include:

  • Brain injury associated with pregnancy or birth, such as asphyxia, low birth weight or prematurity
  • Developmental malformations of the brain
  • Certain metabolic conditions
  • Severe brain infections, such as encephalitis, meningitis or rubella

Lennox-Gastaut Syndrome Doctors and Providers