Pediatric Eosinophilic Colitis (EC)

What is Pediatric Eosinophilic Colitis (EC)?

Children with eosinophilic colitis (EC) have elevated levels of eosinophils (a type of white blood cell that fights allergens) in the large intestine. This leads to inflammation and other complications.

EC is a type of eosinophilic gastrointestinal disorder (EGID) that is closely related to eosinophilic esophagitis (EoE), eosinophilic gastritis (EG) or eosinophilic gastroenteritis (EGE). Like other EGIDs, EC might be associated with other atopic conditions such as food allergies, asthma and atopic dermatitis.

What are the signs and symptoms of Pediatric Eosinophilic Colitis (EC)?

• Abdominal pain
• Anemia 
• Bloody diarrhea
• Diarrhea

What are the causes of Pediatric Eosinophilic Colitis (EC)?

The exact reason why certain individuals have EC is unknown. However, the protein found in cow’s milk is a common trigger of EC inflammation. In many individuals, the trigger of their EC inflammation is unknown. Children with a personal or family history of food allergies may be at higher risk for developing this condition.

How is Pediatric Eosinophilic Colitis (EC) treated?

Treating EC with a comprehensive plan

• The pediatric specialists at UT Southwestern Pediatric Group are experts in diagnosing and treating digestive and nutrition issues in children. We tailor our approach using child-friendly language, equipment and amenities to help the children feel comfortable and at ease. 
• When we see your child for an initial visit, you can expect us to thoroughly review medical records, including surgeries or endoscopies, blood work and previous allergy testing.
• Next steps may involve additional blood tests, endoscopy, allergy testing and imaging. We will engage our entire team in developing a treatment plan. A food elimination diet is a common course of action, and we may introduce steroids and/or medications used to target GI inflammation.