Eosinophilic colitis is a rare disorder that involves elevated levels of eosinophils (a type of white blood cell that fights allergens) in the large intestine causing inflammation that leads to problems with diarrhea or bloody diarrhea.
Children with eosinophilic colitis (EC) have elevated levels of eosinophils (a type of white blood cell that fights allergens) in the large intestine. This leads to inflammation and other complications.
EC is a type of eosinophilic gastrointestinal disorder (EGID) that is closely related to eosinophilic esophagitis (EoE), eosinophilic gastritis (EG) or eosinophilic gastroenteritis (EGE). Like other EGIDs, EC might be associated with other atopic conditions such as food allergies, asthma and atopic dermatitis.
The exact reason why certain individuals have EC is unknown. However, the protein found in cow’s milk is a common trigger of EC inflammation. In many individuals, the trigger of their EC inflammation is unknown. Children with a personal or family history of food allergies may be at higher risk for developing this condition.
Treating EC with a comprehensive plan