
Bradley Edward Weprin, MD
Pediatric Neurosurgeon
Assistant Professor at UT Southwestern Medical Center
Division Director at Children's Health
- Languages Spoken:
- English,

Biography
A father’s heart informs just about everything Dr. Bradley Weprin undertakes as the division director of neurosurgery at Children’s Health℠.
“I’m a dad, so I empathize with the parents of patients, who, like me, want to see their children grow, develop and mature,” he says. “My job as a pediatric neurosurgeon gives me the exciting and rewarding opportunity to care for all different types of problems, from brain surgery to spinal surgery to peripheral nerve surgery, all to make an important impact on a child and a child’s family.”
As director of neurosurgery, Dr. Weprin manages the mission of providing the highest quality care through the strategic use of advanced technology and surgical procedures, including microsurgery, image guidance techniques and brain mapping. The department is one of the busiest neurosurgical practices in North America, often drawing patients from around the world. One of the most complex cases managed by Dr. Weprin and his team was the separation of 2-year-old twins who were conjoined at the head. The separation involved a 34-hour operation and months-long follow-up period.
Because he treats deformities, injuries and pediatric trauma involving the brain, spine or peripheral nerves, parents often think the worst when they receive a referral for a pediatric neurological surgery evaluation. However, helping parents and their children deal with that fear is one of the most satisfying aspects of Dr. Weprin’s career.
Watching a mom and dad smile after their fear has been eased is an incredible feeling.
“Watching a mom and dad smile after their fear has been eased is an incredible feeling,” he says. “And, while not always pleasant, having the privilege to help a family through extremely difficult times makes you realize that you are human and truly experience all that life has to offer.”
Dr. Weprin earned his medical degree from UT Southwestern Medical Center. He completed his internship and residency at the University of Minnesota Hospital and Clinic and his fellowship in pediatric neurosurgery at Children’s Hospital of Alabama. He is certified by the American Board of Neurological Surgery and is a member of the American Society of Pediatric Neurosurgery, the International Society for Pediatric Neurosurgery and the American Association of Sports Medicine.
Outside of his practice, Dr. Weprin enjoys watching his children in their sports activities, as well as running and training for marathons, half marathons and 200-mile relays.
Education and Training
- Medical School
- University of Texas Southwestern Medical Center (1992)
- Internship
- University of Minnesota at Minneapolis (1993), General Surgery
- Residency
- University of Minnesota at Minneapolis (1998), Neurosurgery
- Fellowship
- Children's Hospital of Alabama (1999), Pediatric Neurological Surgery
- Board Certification
- American Board of Pediatric Neurological Surgery,
American Board of Neurological Surgery
Conditions
- Anaplastic Astrocytoma
- Apert Syndrome
- Arachnoid Cyst
- Arterial Dissection
- Arteriovenous Fistula (AVF)
- Arteriovenous Malformations (AVMs)
- Atypical Teratoid Rhabdoid Tumor
- Brain Abscess
- Brain Aneurysms
- Cavernous Malformations
- Cerebral Sinovenous Thrombosis
- Cerebrovascular Disease and Stroke
- Chiari Malformations
- Craniopharyngioma
- Encephalocele
- Ependymoma
- Glioblastoma
- Head Trauma
- Hemorrhagic Stroke
- Hydrocephalus
- Lipomas (Skin Lesions)
- Medulloblastoma
- Moyamoya Disease
- Pfeiffer Syndrome
- Pilocytic Astrocytoma
- Pleomorphic Xanthoastrocytoma
- Spina Bifida (Myelomeningocele)
- Tethered Cord
- Vein of Galen Malformations
- Ventriculomegaly
Treatments
- Baclofen Pump
- Craniectomy
- CyberKnife
- External Ventricular Drain
- Gamma Knife
- Laminectomy
- Management of complex craniofacial anomalies
- Management of hydrocephalus
- Management of spasticity and movement disorders
- Management of spinal dysraphism and repair of spinal cord anomalies
- Myelomeningocele repair
- Neuroendoscopy
- Shunt Placement
- Stereotactic Radiosurgery
- Treatment of all tumors of the central nervous system
Departments and Programs
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Research Interests
Dr. Weprin's research projects include long-term follow-along care for children with acquired brain injuries, radiographic features following Gamma Knife radiosurgery for AVMs in children, treatment of diffuse intrinsic pontine gliomas, radiographic findings of spinal cord injury in inflicted head injury of infants, neurobehavioral and social outcomes of head injuries in adolescents, and determination of infection rates for a particular type of catheter when used in shunt systems for the treatment of hydrocephalus.
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Publications
- Scott WC, Swift DM, Weprin BE. The subgaleal distal catheter technique: An alternative approach for avoiding distal catheter malfunction in posterior fossa cystoperitoneal shunts. Pediatr Neurosurgery. Submitted.
- Lal CV, Mir IN, Kelley E, Weprin BE, Brion LP. Hypomagnesemia Secondary to Cerebrospinal Fluid Losses in a Patient with Congenital Hydrocephalus. J Perinatol 2014;34:640-1.
- Scott WC, Weprin BE, Swift DM. A unifying theory for the multi-factorial origin of hydrocephalus and cerebellar tonsillar herniation in osteopetrosis. J Neurosurgery-Peds. 2014 Oct; 17:1-9.
- Kershenovich A, Silman Z, deRungs D, Koral K, Gargan L, Weprin BE. Tectal Lesions in Children: a long term follow up volumetric tumor growth analysis in surgical and non-surgical cases. Journal Pediatric Neurosurg. Awaiting publication
- Scott WC, Koral K, Margraff L, Klesse L, Weprin BE. Intracerebral schwannomas: a rare disease with varying natural history. Report of 3 cases, J Neurosurg. 2013 July; 12(1):6-12.
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Professional Activities
- American Association of Neurological Surgeons
- American Society of Pediatric Neurosurgeons
- Congress of Neurological Surgeons
- CNS/AANS Joint Section of Pediatric Neurological Surgery
- International Society of Pediatric Neurosurgery
- Children’s Oncology Group
- Hydrocephalus Association
- American Association of Sports Medicine
- Texas Medical Association
- American Medical Association
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Awards and Honors
- D Magazine Best Pediatric Specialist 2010-2013, 2015-2020
- Honorary Fellow 2016, Glasgow NeuroSociety
- Doctors of Distinction Annual Award 2005, Haddassah
Where I Provide Care
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Specialty Center 1 on the Children’s Health Plano Campus
7609 Preston Road Suite Plano, Texas 75024 469-303-7000