Adrenoleukodystrophy (ALD) is a genetic disease that causes problems in a child’s nervous system and adrenal glands.
Adrenoleukodystrophy is a rare, genetic disorder in which the body cannot break down fatty acids in the brain. The resulting buildup of fatty acids leads to a breakdown of the myelin sheath – the insulation covering that protects the nerve fibers in the brain. This makes it impossible for nerves in the body to communicate with the brain. ALD also affects the adrenal gland, which produces important hormones that control metabolism, blood pressure and the body’s responses to stress.
There are three main types of adrenoleukodystrophy:
A disorder in which the adrenal glands do not produce enough hormones.
A condition that causes spinal cord dysfunction, and typically affects young adult males.
A severe form of adrenoleukodystrophy that damages the myelin sheath and prohibits the brain from working properly. This form only affects boys, with symptoms usually starting between ages 2 and 10.
The symptoms of adrenoleukodystrophy depend on the type your child develops.
Adrenoleukodystrophy is caused by a gene mutation on the X chromosome, which is passed on from a mother to her child. The condition is more common in males.
This injection should be used when your child cannot take Hydrocortisone or Prednisone by mouth due to vomiting or unconsciousness. Please utilize this video as a periodic refresher so that if or when you need to give this injection you feel comfortable doing so. After administering Solu-Cortef, you should call 911 or call our office at 214-456-5959. Learn more about hydrocortisone injections in children.