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$$ Ralph John DeBerardinis, MD Division Director at Children's Health Associate Professor at UT Southwestern Medical Center

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UTSW Physician Practicing at Children's Health


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Biography

Biography

Ralph DeBerardinis, M.D., Ph.D., is a Medical Geneticist at Children’s Health℠ and faculty member at UT Southwestern Medical Center. His clinical care focuses on pediatric genetics and newborn screening for metabolic disorders, and his research focuses on the role of altered metabolism in cancer and childhood genetic diseases. He is considered an international leader in research on cancer metabolism.

Dr. DeBerardinis earned his M.D. and Ph.D. at the University of Pennsylvania. He completed residencies in pediatrics and medical genetics and a fellowship in clinical biochemical genetics at Children’s Hospital of Philadelphia.

Dr. DeBerardinis is currently a Professor in the Children’s Medical Center Research Institute (CRI) and Department of Pediatrics at UT Southwestern. He is the Robert L. Moody, Sr. Faculty Scholar, Sowell Family Scholar in Medical Research and the Joel B. Steinberg, M.D. Chair in Pediatrics at UT Southwestern. He serves as Chief of Pediatric Genetics and Metabolism at UT Southwestern and Director of the Genetic and Metabolic Disease Program in the CRI. In 2018 he was appointed as an Investigator in the Howard Hughes Medical Institute.

Dr. DeBerardinis has published more than 170 articles and chapters on the role of perturbed metabolic states in human health and disease. He serves on editorial boards of several major biomedical journals, including eLife and Cancer Discovery. He is a member of the American Association for Cancer Research, Society for Pediatric Research, American Society of Human Genetics and Society for Inherited Metabolic Disorders. He has been elected to the American Society for Clinical Investigation and named to D Magazine’s list of Best Pediatric Subspecialists. Dr. DeBerardinis has trained and advised dozens of medical students, residents, postdoctoral trainees and visiting scientists.

Education and Training

Education and Training

Medical School

University of Pennsylvania School of Medicine (2000)

Residency

Children's Hospital of Philadelphia (2005), General Practice
Departments & Programs

Departments & Programs

Research & Publications

Research & Publications

Research Interests

  • Cancer
  • Genetic disorders in children
  • Inborn errors of metabolism
  • Metabolism

To learn more about Dr. Deberardinis's research, visit the Children’s Medical Center Research Institute at UT Southwestern.

Selected Publications

Professional Activities

Professional Activities

Professional Associations and Affiliations

  • American Society for Clinical Investigation (2013)
  • American Academy of Pediatrics
  • American Association for Cancer Research
  • American Society of Human Genetics
  • Society for Inherited Metabolic Disorders
  • Society for Pediatrics Research

Awards & Honors

Awards & Honors

  • Damon Runyon Cancer Research Foundation Clinical Investigator Award (2011)
  • President’s Research Council Distinguished Young Researcher Award (2008)
  • Soc. for Inherited Metabolic Disorders Neil Buist Award (2008)
  • Sowell Family Scholar in Medical Research (2008)
  • William K. Bowes, Jr. Award in Medical Genetics (2008)
  • CHOP Pediatric Scholars Program & Faculty Honor Roll (2007)