resources
From continuing education to podcasts by our team of experts, keep up with the latest at Children's Health.
RESEARCH & INNOVATION
transforming pediatric health care
Gastroenterology
Uncovering the esophageal microbiome and its role in pediatric esophageal disease
Research led by Children’s Health reveals the esophageal microbiome as an active immunologic environment, with disease-specific microbial patterns that may inform biomarker development, earlier diagnosis and targeted therapies.
Gastroenterology
Technically variant grafts significantly close the gap in pediatric liver transplant access
Pediatric split liver transplant surgery is rare, with only 10 U.S. centers offering it. Children’s Health began using technically variant grafts in 2024 and has since doubled the national average, expanding access and reducing waitlist mortality.
Gastroenterology
First evidence-based guidelines for pediatric IBS and functional abdominal pain
Learn how Children’s Health collaborated on the first-ever global guidelines for pediatric IBS and functional abdominal pain, offering gastroenterologists evidence-based recommendations to improve care for gut-brain interaction disorders.
Gastroenterology
A modeling breakthrough uncovers new clues to biliary atresia
The underlying cause of biliary atresia is poorly understood. A new modeling breakthrough developed with a mix of pediatric cell types reveals the altered cellular crosstalk driving the disease process – and points to a potential treatment target.
Gastroenterology
Data reveals adolescents opt for bariatric surgery over GLP-1RAs
New research reveals metabolic and bariatric surgery (MBS) is increasing among adolescents struggling with obesity – even with GLP-1RAs as a non-surgical option. Partly because barriers to accessing MBS are decreasing.
Gastroenterology
New protocols to diagnose and treat babies with biliary atresia
Learn how the new Biliary Atresia Program at Children’s Health is incorporating faster workups and optimizing treatment to transform care.
Gastroenterology
Case study: New GI and surgery IBD clinic gets a complex pediatric patient into remission
Learn how GI and surgery worked together in a unique multidisciplinary IBD clinic to get a complex pediatric patient into remission.
Gastroenterology
Pediatric Fatty Liver Disease: How an Innovative Approach Reverses NAFLD
Nonalcoholic fatty liver disease (NAFLD) has rapidly become the most common cause of liver disease in children, but the condition can be reversed through an innovative program that includes diet and lifestyle changes.
Gastroenterology
Clinical outcome and microbiome biomarkers predicting success with fiber food introduction in short bowel syndrome
This study aims to understand the pattern of tolerance of dietary fiber in SBS (short bowel syndrome) subjects vs non-SBS subjects.
Gastroenterology
NCT04336722
The primary objective is to evaluate the efficacy of repeated once-daily doses of odevixibat versus placebo in children with biliary atresia (BA) post Kasai hepatoportoenterostomy(HPE) based on survival with native liver after 104 weeks of study treatment.
Gastroenterology
NCT05426733
This is a Phase 3, multi-center, open-label extension study to evaluate the long-term efficacy and safety of a 120 [MICRO-SYMBOL]g/kg/day dose of odevixibat in patients with BA.
Gastroenterology
NCT04862221
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm, randomized, controlled trial of immunosuppressive therapy for children with acute liver failure.
Gastroenterology
Pediatric CRI Studies: Part 1 Assessing Dehydration with Compensatory Reserve Index (CRI) Monitoring in Children with Vomiting and Diarrhea
We want to evaluate whether the CRi measurement may be used to quantify dehydration in a noninvasive manner.
Gastroenterology
Permanent gastric electrical stimulation in children and adolescents
To be able to provide permanent gastric electical stimulation as a treatment option to pediatric patients with drug-refractory nausea and vomiting associated with gastroparesis of diabetic or idiopathic origin.
Gastroenterology
Low Carbohydrate Diet: The Effects on Non Alcoholic Fatty Liver Disease in Obese Teens
Our study is a 6-month prospective randomized controlled trial with outcomes assessment monthly for the first 6 months and a follow up visit at 10-12 months after randomization.
Gastroenterology
NCT01944696
Cycled (intermittent) phototherapy will be compared to continuous (uninterrupted) phototherapy in the treatment of hyperbilirubinemia (newborn jaundice) in extremely low birth weight newborns in a pilot randomized controlled trial.