ESTABLISHING EFFICACY OF AN INPATIENT INTERVENTION AND PHONE APP TO REDUCE SUICIDE RISK
Study ID: STU 112016-057
We aim to randomize 240 adolescents psychiatrically hospitalized for suicidal ideation or a suicide attempt to one of four treatment arms: (1) aSaP + BRiTe+Tau; (2) BRiTe + Tau; (3) aSaP + Tau (4) Tau alone and assess suicidal ideation and behavior at 1, 3, and 6 months post-intake, in order to: 1. assess the relative efficacy of aSaP, BRiTe and the combination on suicidal ideation, non-suicidal self-injury (nSSi), and suicide attempts, and re-hospitalizations. H1: Both aSaP and BRiTe will be superior to Tau alone, and aSaP+BRiTe will be superior to BRiTe or aSaP alone. 2. examine mediators and moderators of treatment outcome H2: The effects of aSaP and BRiTe will be mediated by increases in reasons for living, decreases in dysfunctional emotional regulation, increases in functional emotional regulation, and decreases in implicit associations with death, and will be moderated by previous history of an attempt, and family engagement in treatment. in addition, the impact of BRiTe will be proportional to the frequency of use. 3. To examine the costs and cost efficacy of aSaP and BRiTe and the combination. H3: . Cost per outcome achieved will be lower for each of the interventions (aSaP+BRiTe; aSaP alone; BRiTe alone) compared to Tau at Week 24 follow-up. Cost per outcome achieved will be most advantageous for aSaP+BRiTe.
The inclusion criteria is: 1) The youth is age 12 years 0 months to 17 years 11 months, inclusive at study consent/baseline. 2) The youth is admitted to an inpatient unit for a recent suicide attempt or significant suicidal ideation with a plan or intent. 3) The youth and parent are able to complete assessments in English, and the youth is able to complete therapy in English. 4) The youth has a smartphone, tablet, or device on which the Brite app could be utilized
in this 2-site study (university of Texas Southwestern Medical Center (uTSW) and Western Psychiatric institute and Clinic (WPiC)), we propose to conduct a randomized clinical trial (RCT) in 240 psychiatrically hospitalized suicidal adolescents, examining the single and additive effects of two components of an inpatient unit intervention for suicidal adolescents, as Safe as Possible (aSaP), which focuses on emotion regulation and safety planning, and an emotion regulation/safety plan phone app (BRiTe).