Pediatric Polyarteritis Nodosa (PAN)

Pediatric Polyarteritis Nodosa (PAN)



Polyarteritis nodosa is a rare and often fatal condition that causes vasculitis (inflammation of the blood vessels).

Expanded overview

Polyarteritis nodosa is a life-threatening condition that causes inflammation of the blood vessels. The condition typically affects middle-aged adults and is rarely seen in children.

Inflammation in the small and medium arteries caused by pediatric polyarteritis nodosa can lead to serious damage to organs and body systems, including the heart, joints, kidneys, nervous system and digestive system.


Polyarteritis nodosa in children is caused by an immune system malfunction. It often occurs in children who have Kawasaki disease .


The symptoms of polyarteritis nodosa in children may include:

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