Cerebrocostomandibular syndrome is an extremely rare condition in which a child will have an abnormally small jaw, malformations of the palate, improper tongue position and abnormal rib development.
Cerebrocostomandibular syndrome (CCMS) is a rare condition that affects the jaw, mouth and ribs. Researchers have documented fewer than 100 cases of CCMS.
Most children with CCMS have what’s known as Pierre Robin sequence. This is a set of abnormalities affecting the head and face, including a small lower jaw and a tongue that starts further back than normal that can block the airways.
The difference between Pierre Robin sequence and CCMS is the presence of the rib abnormality. Children usually have 12 pairs of ribs. With CCMS, some ribs may be absent or not form completely. Also, abnormal gaps can occur in the back of the rib cage, which can change the appearance of the chest.
Most cases of CCMS are sporadic and are not a result of an inherited condition. However, some cases are linked to a genetic condition.