Stickler syndrome affects the production of collagen protein in the connective tissue, causing problems with a child’s joints and other organs.
Stickler syndrome is a congenital (from birth) disorder that affects the production of collagen in the connective tissue. Connective tissue is what holds the body together - in the joints, tendons, muscles, bones, organs and skin. Collagen proteins are important in keeping the connective tissue in the joints and organs strong and healthy.
Stickler syndrome is caused by gene mutations that occur while a child is developing in their mother’s womb that affect the production of collagen in a child’s body.
Children with Stickler syndrome may have mild or severe symptoms, depending on the type. Stickler syndrome is a progressive disorder, so your child’s symptoms will become more noticeable or severe as they age. The signs of Stickler syndrome may include: