Focal segmental glomerulosclerosis causes damage to the tiny filters called glomeruli in the kidneys, which can eventually lead to kidney failure.
Focal segmental glomerulosclerosis is one of several conditions that can cause kidney problems by damaging the glomeruli (tiny filtering units located inside the kidneys). The glomeruli help the kidneys remove extra water and waste from the body, while keeping the good proteins and other important nutrients. Conditions that affect the glomeruli are called glomerular diseases.
Focal segmental glomerulosclerosis is a type of glomerular disease that causes scarring in the glomeruli. There are two types of focal segmental glomerulosclerosis:
when the disease has no known cause
when the disease is caused by another condition or medication
In the early stages, there are no symptoms of focal segmental glomerulosclerosis. Later symptoms may include:
American Board of Pediatrics/Nephrology