Pediatric Chronic Kidney Disease (CKD)

Pediatric Chronic Kidney Disease (CKD)



Pediatric chronic kidney disease (CKD) refers to the gradual loss of kidney function over time due to medical conditions that weaken kidney function.

Expanded Overview

Kidneys play many important roles in a child’s overall health. They make urine, and filter water and waste out of the blood. Kidneys also balance salts and minerals that circulate in the blood, and make hormones that control blood pressure and create red blood cells. When the kidney doesn't function properly, it can lead health complications and kidney failure. CKD does not disappear with treatment and often gets worse over time.


Chronic kidney disease in children can result from an acute (sudden) kidney injury that doesn’t improve, or any of the other following causes:


Children in the early stages of chronic kidney disease may not show any symptoms. The following symptoms may not be apparent until the disease is more serious:

  • Blood in urine
  • Burning pain while urinating
  • Dehydration
  • Difficulty sleeping
  • Dry, itchy skin
  • Fatigue
  • Fever
  • Frequent urination, especially at night, and having accidents during the day
  • High blood pressure
  • Muscle cramps at night
  • Pain in the back, side or lower belly
  • Poor appetite
  • Swelling of the feet, ankles, legs or puffy eyes in the morning

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