Pediatric premature adrenarche (PA) is the start of hormonal and physical changes before they normally occur.
Puberty typically occurs between the ages of 10 and 14 for girls and 12 and 16 for boys*. If a child has premature adrenarche, changes will begin around age 8 or 9 when the adrenal gland starts producing hormones.
The exact cause of premature adrenarche is often unknown. It can be a symptom of a condition that causes a hormonal imbalance, such as:
Cushing’s disease – a condition that causes high levels of the hormone cortisol, leading to weight gain.