Current and Future Research - Center for Pectus and Chest Wall Anomalies

Current and Future Research - Center for Pectus and Chest Wall Anomalies

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Research helps us better understand diseases and can lead to advances in diagnosis and treatment.

We know chest wall abnormalities are caused by abnormal growth of the cartilage between the ribs and the sternum.  Current research has shown more than 40% of those diagnosed with Pectus Excavatum have a family member with the diagnosis.

Current Research

The Research Team at the Center for Pectus and Chest Wall Anomalies is currently participating in a national genetic study looking at the variations in genes in families affected by a Pectus diagnosis.  Understanding the genetic differences may help us find ways to determine who is likely to develop and what causes the defect in the first place.  If you have a chest wall anomaly or someone in your family does and you would like to participate in this important research, please contact the Research Team below.

 PB&J (Pectus Brace and Position Justification)

As a center that provides the Dynamic Compression Bracing System for the treatment of Pectus Carinatum, we are conducting a study to determine the best way to treat our patients using this important technology.  We will be measuring and comparing the brace compression pressures between several body positions, such as standing, sitting or lying down or on one’s side, to make sure our patients are receiving the most benefit. 

How to Image with Metal in Your Body (Cardiac MRI)

Our center has been awarded a Discovery Grant from the University of Texas Southwestern Medical Center Department of Surgery to develop a process to use Magnetic Resonance Imaging (MRI), a special type of scanner, to evaluate heart function in patients who have had a surgical repair of their Pectus Excavatum.  

Recent Research 

Kelly RE, Quinn A, Varela P, Redlinger RE, Nussa D, Dysmorphology of Chest Wall Deformities: Frequency Distribution of Subtypes, Arch Bronconeumol .  2013; 49(5):196-200

Cobben JM, Oostra RJ, van Dijk FS, Pectus excavatum and carinatum, European J of Med Genetics 57 (2014) 414-417

Research Team

Lorrie Burkhalter, MPH, CCRC - Program Manager

Gentry Wools, BAS, CCRP - Clinical Research Coordinator

Claudia “Erica” Rivera, MA - Research Associate

Adam Alder, MD, FACS, FAPS - Director, Center for Chest Wall Anomalies