Pediatric Gilbert’s Disease

Pediatric Gilbert’s Disease



Gilbert’s disease is a liver disorder in which bilirubin is not properly processed.

Expanded overview

A fairly common condition, Gilbert’s disease is typically harmless. In children with this condition, the liver does not properly process bilirubin, which is a normal byproduct of the breakdown of red blood cells. This condition is also known as constitutional hepatic dysfunction or familial nonhemolytic jaundice.


A gene mutation that is hereditary (passed down in families) causes Gilbert’s disease.

Risk Factors

There are certain conditions and situations that can lead to increased bilirubin levels. These include:

  • Cold or flu
  • Dehydration
  • Fasting or eating too few of calories
  • Menstruation
  • Not getting enough sleep
  • Stress
  • Vigorous exercise


The only symptom of Gilbert’s disease is jaundice, which is caused by the increased levels of bilirubin in the child’s blood. 

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