Pediatric Eosinophilic Colitis (EC)

Pediatric Eosinophilic Colitis (EC)

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Summary

Eosinophilic colitis (EC) is a condition in which eosinophil – a type of white blood cell – is highly elevated in the large intestine, leading to complications.

Expanded overview

Children with eosinophilic colitis (EC) have elevated levels of eosinophil (a type of white blood cell) in the large intestine. This leads to inflammation and other complications. A child who has EC may also have other eosinophil-associated gastrointestinal diseases, including eosinophilic esophagitis (EoE)  or eosinophilic gastroenteritis.

EC affects both males and females equally. In many cases, symptoms of this condition are apparent before 6 months of age. In most cases of EC that is caused by a cow’s milk protein allergy, the child ceases showing most symptoms by around 1 year of age.

Causes

In many cases, the cause of EC is unknown. However, the protein found in cow’s milk sometimes worsens symptoms. Children with a personal or family history of food allergies may be at higher risk for developing this condition.

Symptoms

Signs and symptoms of EC may include:

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