Pediatric Glioblastoma

Pediatric Glioblastoma



Glioblastomas (GBM) are tumors in the brain or spinal cord that are usually highly malignant (cancerous).

Expanded overview

Glioblastomas (GBM) are tumors that develop from astrocytes (star-shaped cells that comprise the supportive tissue) of the brain. Because GBM cells reproduce rapidly and are supported by a large network of blood vessels, they are usually cancerous. GBM tumors put extra pressure on the brain, causing the related symptoms.


There are two types of GBM:

  • Primary (de novo) – The most common type of GBM, this type usually forms quickly and children rapidly begin to show symptoms.
  • Secondary – This type of GBM usually grows more slowly, but is still quite aggressive. In many cases, they begin as low-grade tumors (slow rate of growth and high rate of survival) that turn into a higher grade over time.


Signs and symptoms of GBM can include:

  • Changes in vision
  • Drowsiness
  • Headache
  • Nausea
  • Problems with memory
  • Problems with speech
  • Vomiting
  • Weakness on one side of the body

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