Glioblastomas (GBM) are tumors in the brain or spinal cord that are usually highly malignant (cancerous).
Glioblastomas (GBM) are tumors that develop from astrocytes (star-shaped cells that comprise the supportive tissue) of the brain. Because GBM cells reproduce rapidly and are supported by a large network of blood vessels, they are usually cancerous. GBM tumors put extra pressure on the brain, causing the related symptoms.
There are two types of GBM:
- Primary (de novo) – The most common type of GBM, this type usually forms quickly and children rapidly begin to show symptoms.
- Secondary – This type of GBM usually grows more slowly, but is still quite aggressive. In many cases, they begin as low-grade tumors (slow rate of growth and high rate of survival) that turn into a higher grade over time.
Signs and symptoms of GBM can include:
- Changes in vision
- Problems with memory
- Problems with speech
- Weakness on one side of the body