Food protein-induced enterocolitis syndrome (FPIES) is a food allergy that occurs in the digestive tract and impacts mostly infants and young children.
FPIES is type of food allergy that impacts mostly infants (0 to 1 year*) and young children (1 to 5 years**). It occurs when the digestive tract (also known as the gastrointestinal or GI tract), including the small intestine and colon, become inflamed and swollen in response to an allergic reaction.
FPIES is typically seen within the first few weeks or months of life, but can occur later if a child has only been breastfed. Children can, but will not always, outgrow FPIES by age 3.
FPIES is caused by ingesting a food or drink that triggers an allergic reaction.
Triggers vary between children, as do allergies and the severity of the reaction to each trigger. Triggers can include:
Dairy and soy, including infant formulas
Rice, oats and barley
Green beans and peas
Sweet potatoes and squash
Chicken and turkey
Symptoms of FPIES include:
Failure to thrive (trouble gaining weight)
Intense and frequent vomiting
Lack of energy (lethargy)
Anaphylactic shock symptoms
Anaphylactic shock (also called anaphylaxis) is a severe allergic reaction that comes on rapidly and must be treated immediately. Symptoms include: