This study will be a non-blinded, non-randomized trial. There will be two (2) sites with a limit of fifteen (15) subjects at each site. (up to thirty (30) total subjects are planned.) each subject will have Tympanoseal placed during a surgical procedure. evaluations will be taken at baseline and up to three evaluations at 4, 10 and 16 weeks. if tympanic healing is noted at any visit, then the subject may exit the study without need for additional follow-up evaluations. Screening data will be reviewed to determine subject eligibility. Subjects who meet all inclusion criteria and none of the exclusion criteria will be entered into the study. all subjects will be treated with surgically implanted Tympanoseal, either unilaterally or bilaterally as needed. Total duration of subject participation will be up to 16 weeks post-procedure and total study duration is estimated to be 6 months.