Brad Edward Weprin, MD $$

Division Director, Neurosurgery

Professor at UT Southwestern Medical Center
Division Director at Children's Health

Languages Spoken:


UT Southwestern Pediatric Group

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Dr. Bradley Weprin is an accomplished pediatric neurosurgeon and program administrator. He has a successful record of managing pediatric neurosurgical services that deliver excellence in care, patient experience, and academic pursuits. The primary focus of his career has been in the delivery of the best medical care. As director of neurosurgery at Children’s Health℠, he manages the mission of providing the highest quality care through the strategic use of advanced technology and surgical procedures, analysis of outcomes, and teamwork. The division is one of the busiest pediatric neurosurgical practices in North America, often drawing patients from around the world. One of the most complex cases managed by Dr. Weprin and his team was the separation of 2-year-old twins who were conjoined at the head. The separation involved a 34-hour operation and months-long follow-up period.

Because he treats deformities, injuries and pediatric trauma involving the brain, spine or peripheral nerves, parents often think the worst when they receive a referral for a pediatric neurological surgery evaluation. However, helping parents and their children deal with that fear is one of the most satisfying aspects of Dr. Weprin’s career. He is passionate about eliminating barriers to care, addressing the social determinants of health in pediatric neurosurgical care, and improving delivery of high quality and specialized pediatric health care. He still boasts, however, that his greatest accomplishment has been as a father to his two young adult children.

Dr. Weprin earned his medical degree from UT Southwestern Medical Center. He completed his internship and residency at the University of Minnesota Hospital and Clinic and his fellowship in pediatric neurosurgery at Children’s Hospital of Alabama. He completed his Masters of Health Care Management (medical MBA) at Harvard in 2021. He is certified by the American Board of Neurological Surgery and the American Board of Pediatric Neurosurgery. He is on the Executive Committee of the American Society of Pediatric Neurosurgery and is a member the International Society for Pediatric Neurosurgery, AANS/CNS Joint Section of Pediatric Neurosurgery and the American Association of Sports Medicine.

Outside of his practice, Dr. Weprin enjoys watching his children in their sports activities, as well as running and training for marathons, half marathons and 200-mile relays.

Education and Training

Medical School

University of Texas Southwestern Medical Center (1992)


University of Minnesota at Minneapolis (1993), General Surgery


University of Minnesota at Minneapolis (1998), Neurosurgery


Children's Hospital of Alabama (1999), Pediatric Neurological Surgery

Board Certification

American Board of Pediatric Neurological Surgery


  • Baclofen Pump
  • Craniectomy
  • CyberKnife
  • External Ventricular Drain
  • Gamma Knife
  • Laminectomy
  • Management of complex craniofacial anomalies
  • Management of hydrocephalus
  • Management of spasticity and movement disorders
  • Management of spinal dysraphism and repair of spinal cord anomalies
  • Myelomeningocele repair
  • Neuroendoscopy
  • Shunt Placement
  • Stereotactic Radiosurgery
  • Treatment of all tumors of the central nervous system
  • Research Interests

    Dr. Weprin's research projects include long-term follow-along care for children with acquired brain injuries, radiographic features following Gamma Knife radiosurgery for AVMs in children, treatment of diffuse intrinsic pontine gliomas, radiographic findings of spinal cord injury in inflicted head injury of infants, neurobehavioral and social outcomes of head injuries in adolescents, and determination of infection rates for a particular type of catheter when used in shunt systems for the treatment of hydrocephalus.

  • Publications

    • Scott WC, Swift DM, Weprin BE.  The subgaleal distal catheter technique: An alternative approach for avoiding distal catheter malfunction in posterior fossa cystoperitoneal shunts.  Pediatr Neurosurgery. Submitted.
    • Lal CV,  Mir IN, Kelley E, Weprin BE, Brion LP.   Hypomagnesemia Secondary to Cerebrospinal Fluid Losses in a Patient with Congenital Hydrocephalus. J Perinatol 2014;34:640-1.
    • Scott WC, Weprin BE, Swift DM.  A unifying theory for the multi-factorial origin of hydrocephalus and cerebellar tonsillar herniation in osteopetrosis.  J Neurosurgery-Peds. 2014 Oct; 17:1-9.
    • Kershenovich A, Silman Z, deRungs D, Koral K, Gargan L, Weprin BE. Tectal Lesions in Children: a long term follow up volumetric tumor growth analysis in surgical and non-surgical cases. Journal Pediatric Neurosurg. Awaiting publication
    • Scott WC, Koral K, Margraff L, Klesse L, Weprin BE.  Intracerebral schwannomas: a rare disease with varying natural history. Report of 3 cases, J Neurosurg. 2013 July; 12(1):6-12.
  • Professional Activities

    • American Association of Neurological Surgeons
    • American Society of Pediatric Neurosurgeons
    • Congress of Neurological Surgeons
    • CNS/AANS Joint Section of Pediatric Neurological Surgery
    • International Society of Pediatric Neurosurgery
    • Children’s Oncology Group
    • Hydrocephalus Association
    • American Association of Sports Medicine
    • Texas Medical Association
    • American Medical Association
  • Awards and Honors

    • D Magazine Best Pediatric Specialist 2010-2013, 2015-2020
    • Honorary Fellow 2016, Glasgow NeuroSociety
    • Doctors of Distinction Annual Award 2005, Haddassah

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