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The Caruth Center


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Children’s Medical Center is acclaimed for excellence in clinical care but is equally committed to the pursuit, development and application of new knowledge to drive improvements in patient care and effective treatments and cures. 

One of a Kind

The Caruth Center for Pediatric Translational Clinical Research is the first of its kind in the nation with a concentration on diseases specific to children, including congenital abnormalities, cancers that mainly affect children, and certain pediatric viral infections.


That commitment on the part of Children’s to lead the way in pediatric research is what drives the W.W. Caruth, Jr. Center for Pediatric Translational Clinical Research. The Caruth Center has become the cornerstone of translational research enterprise at Children's. Ralph Waldo Emerson exorts us to “be an opener of doors for such as come after thee.” The Caruth Center has been that “opener of doors” at Children’s Medical Center as evidenced by the tremendous research that is being done in order to address the vital health needs of the children we serve.


Children’s multidisciplinary setting provides physicians the opportunity to investigate childhood diseases in a controlled environment. Translational clinical research is the process of converting basic scientific discoveries made at the laboratory bench into clinical innovations and new therapies that can help patients.

The first effort to develop a translational clinical research infrastructure was the W.W. Caruth Jr. Center for Pediatric Translational Clinical Research.  The Caruth Center was initially funded in 2004 by a $5 million endowment from the W.W. Caruth Jr. Foundation. Today, The Caruth Center is the cornerstone of translational research enterprise at Children's. 

Areas of Service

The Caruth Center funds investigators' research based on recommendations from the Children's Clinical Research Advisory Committee (CCRAC), develops and implements research studies, and administers research to ensure compliance with federal and state regulations and hospital policy.