Pediatric Urology: Research & Education

Research

A documentation of procedure success rates, complication rates and satisfaction results, may benefit future children with various genitourinary disorders. The results may also present the means to identify or consider alternative treatments. Study results of patient satisfaction may provide investigators with information identifying opportunities to improve or enhance the existing surgical techniques. In addition, they may provide more or better information that can be provided to future patients and their parents prior to making treatment decisions.

The correlation between clinical disease status, previous treatments, and research findings from the various studies performed will hopefully provide insight into mechanisms of genitourinary disease pathogenesis, progression, and treatment and, therefore, be of tremendous benefit to individuals suffering from benign or malignant genitourinary diseases.

  • Clinical trials

    The Center for Pediatric Urology at Children’s Medical Center is currently involved in the following scientific molecular biology, clinical long-term follow-up, and technology trials:

     

    • Long-term follow-up after tubularized incised-plate urethroplasty for proximal hypospadias

    • Clinical evaluation of undescended testes and retractile testes

    • SLING procedures without bladder augmented in children with myelomeningocele

    • Genetic etiology of testicular torsion and vanished testes

    • The Insl-3 gene and LGR8 and their role in the etiology of human cryptorchidism

    • Genes of male determination and their role in the etiology of intersex disorders

    • Human female reproductive duct anomalies “Mullerian Duct Anomalies”

    • Stone disease in children and their families

    • Establishment of pediatric genitourinary blood, tissue, urine, serum, and DNA repository

    • Patients with 13q deletion syndrome and/or anorectal urogenital malformations

    • Outcomes of pediatric laparoscopic genitourinary surgery

    • Clinical evaluation of pediatric urolithiasis

    • Investigation of Ureterocele Injection Retrograde Uretergram Procedure

    • Clinical Evaluation of Hypospadias

    • Evaluation of Medullary Nephrocalcinosis in Children With Ultrasound Imaging (US) and Computerized Tomography (CT)

    • Genetic Basis of Exstrophy and Epispadias

    • Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular Torsion

    • Autologous Buccal Mucosa Vaginoplasty

    • Renal Scarring on Dimercaptosuccinic Acid (DMSA) Renography

    • Genetic Basis of Prune Belly Syndrome

    • Signals during mammalian urogenital-anorectal midline development

    • Hidden Incision Endoscopic Surgery (HIdES℠): Description of the Technique and Surgical Applications

    • Genetic Basis of VATER/VACTERL Association

    • Impact of Percutaneous Biopsy and/or Partial Nephrectomy on Outcomes in Patients with Wilms' Tumor

    • Children's Medical Center DNA/Cell/Tissue Repository (CMCDR)

    • Pediatric Urological Disorders Registry

    • Evaluating Penile Measurements in Boys With and Without Genital Abnormalities

    • Pediatric Urinary Stones:  A Pediatric Health Information System Database Study

    • The Role of the EphB-EphrinB Bidirectional Cell-Cell Signaling Pathway in the Developing Penis

    • The Evaluation of the Basis of Pediatric Voiding Dysfunction

    • Self-esteem and feelings of loss and shame in adolescents with testicular loss due to testicular torsion

    • Evaluating Clinical Predictors of Testicular Torsion and Testicular Viability in Boys Presenting to the Emergency Department with “Acute Scrotum”.

  • Residencies, Fellowships & Continuing Ed.