CCBD: Research
As a result of its close affiliation with UT Southwestern Medical Center at Dallas, the Center for Cancer and Blood Disorders is home to groundbreaking basic science and clinical research in pediatric hematology and oncology.
Basic Science Research
- Defining novel cancer genes and understanding the developmental biology of tumors using the zebrafish system
- Understanding the role of microRNAs in rhabdomyosarcoma
Basic Science Research Highlights
- More than $3 million in annual grant support from agencies and organizations such as National Institutes of Health, American Cancer Society, Centers for Disease Control and Prevention, Texas Department of Health, Lance Armstrong Foundation, Children’s Cancer Fund and Wipe Out Kids’ Cancer.
- Faculty currently supported by several prestigious R01 research grants from the NIH.
Clinical Research
The CCBD is nationally recognized for its clinical research excellence in some of the clinical research highlights include being:
- One of the 15 largest centers in the 230-member Children's Oncology Group (COG), which develops national treatment protocols for children with cancer.
- One of only 20 centers nationally approved by the COG to employ novel Phase I experimental cancer drugs to children with advanced malignancy.
- Site of Dallas' first umbilical cord transplant and Texas' first bone marrow transplant for a child with sickle cell disease.
- Site of the Southwestern Comprehensive Sickle Cell Center, and applicant of multiple grants from the National Institutes of Health, which supports investigator-initiated and multi-center collaborative studies involving children with sickle cell disease.
- One of only 18 institutional sites in the NIH-supported Hemostasis-Transfusion Medicine Clinical Trials Network.
- One of two CDC-funded National Resource Centers for Diamond Blackfan Anemia.
- International center for IPT research accomplishment in immune thrombocytopenic and hereditary spherocytosis.
