Bleeding Disorders and Thrombosis: Programs and Treatments

We currently manage more than 175 children with established bleeding disorders and evaluate nearly 100 children each year for potential bleeding conditions. In addition, we treat and counsel nearly 100 new patients a year with thrombosis or thrombophilia. We specialize in the diagnosis and management of children and adolescents with the following conditions:


  • Congenital FVIII and IX deficiency
  • von Willebrand disease
  • Qualitative disorders of platelets
  • Other hereditary bleeding disorders
  • Assessment of children suspected of having a bleeding disorder on the basis of an abnormal laboratory test (prolonged PTT) or signs/symptoms (recurrent epistaxis, easy bruising, positive family history, etc.)


  • Venous and arterial thrombosis
  • Catheter-related thrombosis
  • Familial prothrombotic disorders, including Protein C & S deficiency and Factor V Leiden & Prothrombin G20210A mutations.

Program Highlights

  • A 340B program federally funded by the Centers for Disease Control and Prevention and the Maternal and Child Health Bureau
  • Management of more than 175 children with bleeding disorders annually
  • Treat and manage more than 100 children with thrombosis or thrombophilia annually  
  • No. 1 enrollment center in the United States in the International Pediatric Stroke Study  
  • Developed one of the first guidelines for diagnosing non-sickle cell stroke in children 
  • Close affiliation with the Department of Pediatric Dentistry provides comprehensive and safe dental care for children with bleeding disorders and those on chronic anticoagulation
  • Affiliation exists with UT Southwestern’s diagnostic hemostasis laboratory and the adult component of UT Southwestern’s hemophilia program
  • We participate in a 340B Drug Pricing Program, a federal discount program available to designated Hemophilia Treatment Centers
  • Outpatient management of anticoagulation therapy
  • Development of multidisciplinary guidelines for treatment of acute stroke and participation in a comprehensive long-term follow-up clinic for children with stroke
  • Community outreach:
    • Nurse coordinators’ school visits and lectures to students and staff
    • Education for community physicians and families with inherited thrombophilia about diagnosis, screening and prevention of thrombosis
    • Education for community physicians about diagnosis and treatment of bleeding disorders
    • Active participation and support of NHF and the local chapter, TexCen
    • Participation in a yearly Education Day for Families
  • In July 2013, 33 Gill Center patients attended Camp Ailihpomeh, the week-long summer camp for children in Texas with hemophilia. In addition, members of our team have served as the camp director or co-director for the last four years.
  • Children's participates in the nationwide "Universal Data Collection" project, sponsored by the Centers for Disease Control, which monitors two major complications of bleeding disorders — blood-borne disease and joint disease.
  • Children's is an internationally known leader in research in hemophilia/thrombophilia and other inherited hemorrhagic/thrombotic disorders including catheter-related complications and arthroscopic synovectomy.
  • A member of the Alliance of Five international research group, along with The Hospital for Sick Children in Toronto, Children's Hospital of Philadelphia, Emory University and the University of Montreal.

Contact Cancer and Blood Disorders


Contact Cancer and Blood Disorders at Legacy


Contact the Cancer and Blood Disorders Referral Coordinator