W. W. Caruth Jr. Center for Pediatric Translational Clinical Research

While Children’s Medical Center is known for the excellence of the clinical care it provides patients, we are equally committed to the pursuit, development and application of new knowledge that drives improvements in patient care and effects treatments and cures. We call that endeavor “translational clinical research” – that process of converting basic scientific discoveries made at the laboratory bench into clinical innovations that can be delivered to patients at the bedside.

That commitment on the part of Children’s to lead the way in pediatric research is what drives the W.W. Caruth, Jr. Center for Pediatric Translational Clinical Research. The Caruth Center has become the cornerstone of translational research enterprise at Children's. Ralph Waldo Emerson exorts us to “be an opener of doors for such as come after thee.” The Caruth Center has been that “opener of doors” at Children’s Medical Center as evidenced by the tremendous research that is being done in order to address the vital health needs of the children we serve.

The first effort to develop a translational clinical research infrastructure has been the W.W. Caruth Jr. Center for Pediatric Translational Clinical Research.  The Caruth Center - initially funded in 2004 by a $5 million endowment from the W.W. Caruth Jr. Foundation.  Since 2004, additional funds of approximately $10 million have flowed to the Center from Children's.

Specific areas of service offered by the Caruth Center include (1) funding of Fellows, Junior and Senior investigators' research through the Children's Clinical Research Advisory Committee (CCRAC) mechanism; (2) research study development and operation; and (3) administration of research and ensuring compliance with federal and state regulations and hospital policy.