Children's participates in hypothermia trial

November 02, 2010

Children's and UT Southwestern Medical Center announced that the Perot Family Center for the Care of Brain and Nerve Injuries at Children's has been chosen to participate in a clinical trial to study the effectiveness of induced hypothermia to treat brain swelling in children with traumatic brain injuries.

Children's was selected with the medical school as one of 12 sites participating in the trial. The study is led by Children's Hospital of Pittsburgh with $11.5 million from the National Institutes of Health.

"It's been proven that this therapy is safe. Now we need to affirm that cooling these children helps to prevent brain swelling and potentially improves their lives after a life-altering brain injury," said Dr. Pam Okada, associate professor of pediatrics at UT Southwestern, emergency medicine physician at Children's and lead investigator on the trial.

As the Southwest's only pediatric designated Level I trauma center, Children's receives the type of patients who would qualify for the study. Patients selected to receive hypothermia will be cooled between 89 and 90 degrees Fahrenheit using cooling blankets and/or cooled saline. The community can provide feedback at